3 edition of Nucleic Acid Chemistries and Related Technologies found in the catalog.
Nucleic Acid Chemistries and Related Technologies
October 31, 2009
Written in English
|The Physical Object|
|Number of Pages||600|
The MagMAX Total Nucleic Acid Isolation Kit is designed for the rapid, high-throuphput purification of RNA and genomic DNA from a variety of samples including viral, blood, and bacterial samples. It includes zirconia beads for the mechanical disruption of difficult pathogens. RNA purified using the. Natural oligonucleotides have many rotatable single bonds, and thus their structures are inherently flexible. Structural flexibility leads to an entropic loss when unwound oligonucleotides form a duplex with single-stranded DNA or RNA. An effective approach to reduce such entropic loss in the duplex-formation is the conformational restriction of the flexible phosphodiester linkage and/or sugar.
This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of. Product Specs; Item Maxwell® CSC 48 Instrument; Company Promega; Price Supplier Page View Company Product Page; Catalog Number AS; Quantity EA; Dimensions (WxDxH) 21 x 21 x 14 in ( x x mm); Number of Samples Up to 48; Processing Time 40–60 minutes (depending on sample type and method); UV Lamp Average lifetime approximately 9, hours, length mm, .
In other words, some chemistries of metabolism must be of prebiotic origin and should have been established prior to peptide bond biosynthesis and nucleic acid replication. Cellular metabolism is driven by a complex collection of enzymes, most made solely of proteins and few also involving nucleic acids (e.g., the RNase P complex) . Nuclein is the material found in the nucleus, consisting mainly of nucleic acids, protein, and phosphoric acid. In , Richard Altmann investigated the chemical properties of nuclein. He found it behaved as an acid, so the material was renamed nucleic acid. Nucleic acid .
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Nucleic Acid Probe. PNAs are oligonucleotide analogues in which the natural phosphodiester backbone is replaced by neutral amide linkages (of N-(2-aminoethyl)glycine), increasing their permeation through lipid bilayers (Corey, ; Nielsen, ).
From: Methods in Cell Biology, Related terms: Peptide Nucleic Acid; Fluorescence in Situ. Chemical aspects of nucleic acids come to the fore in the last third of the book, with description of interactions of small molecules with nucleic acids, protein-nucleic acid interactions and techniques used to analyse nucleic acids.
In summary, this book provides an excellent overview of the chemistry and biology of nucleic acids, at a level /5(6). Nucleic Acids Book. A free online book on Nucleic Acid Chemistries and Related Technologies book chemistry and biology of nucleic acids, written by Prof.
Tom Brown and Dr Tom Brown (Jnr). The book is ideal for chemistry and biology students and also provides practical information for researchers working in the lab. Nucleic acid structure. Importantly, this new method is compatible with any nucleic acid chemistry and their discovery includes novel RT enzymes for XNA chemistries for which no RT enzyme previously existed.
At the intersection of nucleic acid and boron chemistries lies a thriving world of possibilities. During the past decades, the merging of these research domains has led to fascinating discoveries in different fields ranging from material to medical sciences.
In recent years the interplay of these two worlds. Nucleic acid, naturally occurring chemical compound that is capable of being broken down to yield phosphoric acid, sugars, and a mixture of organic bases (purines and pyrimidines).Nucleic acids are the main information-carrying molecules of the cell, and, by directing the process of protein synthesis, they determine the inherited characteristics of every living thing.
The Chapter of Biotechnology—Nucleic Acid Technology Aug Antibody Engineering Research Antibody Discovery, biotechnology, nucleic acid biolabs Nucleic acid, as one of the most basic substance of life, is a kind of biological macromolecular compound that polymerized through a large number of nucleotides, of life, which is widely.
Antonio Blanco, Gustavo Blanco, in Medical Biochemistry, Abstract. Nucleic acids (NA) contain the genetic information and play a key role in protein biosynthesis. They are formed by the polymerization of units called nucleotides, which consist of a nitrogenous base, an aldopentose, and phosphoric base can be a pyrimidine: thymine (T), cytosine (C), and uracil (U); or a purine.
AEGEA has a total of 11 issued US patents related to nucleic acid technologies, plus foreign equivalents. One of AEGEA’s patents for rare mutation detection is already validated and in clinical use in identifying biomarkers in cancer patients.
More t patient samples have been analyzed with a publicly listed (NASDAQ) company. OUR MARKETS. Within other case, little men and women like to read book Bioorganic Chemistry: Nucleic Acids (Topics in Bioorganic and Biological Chemistry).
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Here, you’ll find a range of nucleic acid extraction kits that generate high yields from many sample types. From single-prep manual solutions, to cartridge-based Maxwell® Systems, to plate-based processing compatible with high throughput liquid handling systems—Promega chemistries cover the range of your purification needs.
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This book provides a comprehensive overview of PCR theory, instrumentation and methods. The book represents an excellent, detailed guide for anyone interested in the development and use of PCR technology. It is a recommended purchase for all microbiology and molecular biology laboratories and university libraries.
In any sample, a scientist’s journey to extract nucleic acids poses a series of challenges. Beyond overcoming those obstacles, a scientist seeks ways to simplify the process through automation and integration. Ultimately, the connection of steps in a nucleic-acid workflow determines the outcome and how broadly a technique can be applied.
Nucleic Acids. Nucleic acid is a macromolecule that is found in the acid insoluble fraction of any living tissue. Together with polysaccharides and polypeptides these comprise the true macromolecular fraction of any living tissue or cell.
For nucleic acids, the building block is a nucleotide,e. nucleic acids are polymers of nucleotides. Abingdon Health’s PCRD nucleic acid lateral flow immunoassays (NALFIA) are for use alongside isothermal amplification techniques. Results are available in 10 minutes making them the perfect solution for rapid detection of nucleic acids for point of care testing.
Nucleic Acid Therapeutics is the leading journal in its field focusing on cutting-edge basic research, therapeutic applications, and drug development using nucleic acids or related compounds to alter gene expression.
The Journal examines many new approaches for using nucleic acids as therapeutic agents or in modifying nucleic acids for therapeutic purposes including: oligonucleotides, gene.
About. I am a passionate sales professional with over 22 years of experience in the genomics industry, my specific expertise is in synthetic nucleic acid : Nucleic Acid Chemistry Sales. The reader is methodically introduced to the structure and biosynthesis of RNA and DNA; nucleic acids found in viruses; and biosynthesis of mononucleotides.
An account of nucleases and related enzymes is also given. A chapter on the precise mechanism by which nucleic acids are broken down in the cell concludes the book. Products. Discovery & Translational Research. DNA & RNA Purification. DNA. Cell-Free DNA; DNA Clean Up; Genomic DNA; Microbial DNA; Plasmid DNA; RNA.
Cell-Free RNA.Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy.
With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic.Bright prospects for future success motivate investing in genomic technology development, specifically for novel nucleic acid sequencing methodologies.
Objectives NHGRI seeks to fund research efforts in novel chemistries, physical approaches and instrumentation for DNA and direct RNA sequencing.